Homework Help | Explain the etiology and pathophysiology of each disorder.

Choose two GI disorders and discuss the following:
1) Ulcerative Colitis 2) Chron’s Disease

1. Explain the etiology and pathophysiology of each disorder.
2. Describe the clinical manifestations and signs/symptoms the nurse assesses for.
3. Compare and contrast the two disorders.
4. Discuss the nursing implications for treatment.
5. Explain the effects of age related to the disease.
6. List one evidence-based resource the nurse can use to advance his/her knowledge of the disease. 7. Provide a brief summary of something you learned from this resource.

MODEL ANSWER

Gastrointestinal Disorders

Ulcerative Colitis is a disease that causes inflammation and sores in the digestive tract and is triggered by an abnormal immune | PLACE YOUR ORDER NOW AT writtask.com | and symptoms linked to it include abdominal pain, rectal bleeding, fever, fatigue, bloody diarrhea, and weight loss.

Chron’s disease is an illness that causes inflammation in different parts of the digestive tract in different | PLACE YOUR ORDER NOW AT writtask.com | cause for the disease, but factors such as stress, diet, a malfunctioning immune response, and genes are linked to its | PLACE YOUR ORDER NOW AT writtask.com | include malnutrition, fatigue, severe diarrhea, weight loss, and abdominal pain.

Ulcerative Colitis and Chron’s disease are inflammatory bowel diseases (IBDs) and have the same | PLACE YOUR ORDER NOW AT writtask.com | also have some | PLACE YOUR ORDER NOW AT writtask.com | Colitis involves the continuous and complete inflammation of the colon. In the case of Chron’s disease, there can be several healthy parts between the inflamed portions of the colon. Secondly, Ulcerative Colitis only affects the colon’s inner lining, but Chron’s disease can affect all the layers of the intestinal walls.

The recommended medication includes anti-inflammatory drugs, pain relievers, immune system | PLACE YOUR ORDER NOW AT writtask.com | implication in the treatment phase is the need to analyze the medication and the patient’s history and assess any possible drug interactions that may do more harm or be fatal for the patient.

The article by Cleynen et al. (2016) studies the relationships that these two IBDs have as far as biological relations are | PLACE YOUR ORDER NOW AT writtask.com | that while genetics is a factor in whether an individual develops the disease, especially if they possess the three loci associated with IBD’s Subphenotypes, it is not yet a definitive cause of the disease.

References

Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., … & Brant, S. R. (2016). Inherited determinants of Crohn’s disease and ulcerative colitis phenotypes: a genetic association study. The Lancet, 387(10014), 156-167. https://doi.org/10.1016/S0140-6736(15)00465-1

D’Haens, G., Vermeire, S., Lambrecht, G., Baert, F., Bossuyt, P., Pariente, B., … & Van Hootegem, P. (2018). Increasing infliximab dose based on symptoms, biomarkers, and serum drug concentrations does not increase clinical, endoscopic, and corticosteroid-free remission in patients with active luminal Crohn’s disease. Gastroenterology, 154(5), 1343-1351. https://doi.org/10.1053/j.gastro.2018.01.004

MayoClinic. (2019, December 24). Ulcerative Colitis – symptoms, and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/symptoms-causes/syc-20353326

Tiao, D. K., Chan, W., Jeganathan, J., Chan, J. T., Perry, J., Selinger, C. P., & Leong, R. W. (2017). Inflammatory bowel disease pharmacist adherence counseling improves medication adherence in Crohn’s disease and ulcerative ColitisColitis. Inflammatory bowel diseases, 23(8), 1257-1261. https://doi.org/10.1097/MIB.0000000000001194