Describe the chronic relapsing inflammatory bowel diseases (ulcerative colitis and Crohn disease), and summarize the pathophysiology, clinical manifestations, evaluation, and treatment recommendations for each.
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Write My Essay For MeAdvanced Physiology and Pathophysiology
Ulcerative Colitis (UC)
Ulcerative Colitis is a chronic inflammatory bowel disease, that causes ulcers and inflammation in the digestive tract. It is a condition that affects the innermost lining of the large intestine | PLACE YOUR ORDER NOW AT writtask.com | by autoimmune conditions and | PLACE YOUR ORDER NOW AT writtask.com | and symptoms associated with UC include rectal pain and bleeding, fatigue, fever, inability to defecate, abdominal pain, cramping, weight loss, and diarrhea with blood or pus.
Several tests and procedures help to evaluate and diagnose UC. One of the primary tests is the stool and blood tests, which help to rule out the probability of bacterial or | PLACE YOUR ORDER NOW AT writtask.com | will need to undergo endoscopic procedures, such as a colonoscopy and sigmoidoscopy, which will give the doctor a clear idea of how advanced the | PLACE YOUR ORDER NOW AT writtask.com | suggested treatment protocols are dependent on the advancement of the UC in the patient. In minor cases, the treatment protocol involves drug | PLACE YOUR ORDER NOW AT writtask.com | medications recommended for this condition include anti-inflammatory drugs, immune system suppressors, and pain relievers. However, in life-threatening cases the best treatment protocol is surgery.
Crohn’s Disease
Crohn’s disease is a chronic relapsing inflammatory bowel disease caused by an autoimmune system and genetics. Some of the common signs and symptoms include blood in the stool, reduced appetite and weight loss, fever, fatigue, mouth sores, and | PLACE YOUR ORDER NOW AT writtask.com | condition and understand its severity, the patients need to go through several procedures, such as a colonoscopy, MRI, capsule endoscopy, balloon-assisted enteroscopy, and a | PLACE YOUR ORDER NOW AT writtask.com | physician will need blood and stool tests to check for anemia and rule out the possibility of parasites.
Since there is currently no treatment for Crohn’s disease, drug therapy helps the patient control the symptoms and alleviates the | PLACE YOUR ORDER NOW AT writtask.com | prescribed for this condition include anti-inflammatory drugs, immune system suppressants, biologics, and | PLACE YOUR ORDER NOW AT writtask.com | drug and nutrition therapy fail to alleviate the symptoms, then the next best treatment protocol is surgery.
References
Gajendran, M., Loganathan, P., Catinella, A. P., & Hashash, J. G. (2018). A comprehensive review and update on Crohn’s disease. Disease-a-month, 64(2), 20-57.
Le Berre, C., Ananthakrishnan, A. N., Danese, S., Singh, S., & Peyrin-Biroulet, L. (2020). Ulcerative colitis and Crohn’s disease have a similar burden and goals for treatment. Clinical Gastroenterology and Hepatology, 18(1), 14-23.
Ozawa, T., Ishihara, S., Fujishiro, M., Saito, H., Kumagai, Y., Shichijo, S., … & Tada, T. (2019). Novel computer-assisted diagnosis system for endoscopic disease activity in patients with ulcerative colitis. Gastrointestinal Endoscopy, 89(2), 416-421. https://doi.org/10.1016/j.gie.2018.10.020