ASSIGNMENT HELP | Advanced Pharmacology Discussion

Melina is a 36-year-old female with complaints of excessive fatigue, muscle aches, difficulty sleeping, weight gain, and hair loss in the past six months. She recently lost her job as a clerk and is under a lot of stress. She denies taking any medication and denies any medical history. She is crying at the clinic today and tells you that she does not feel right. Her labs demonstrate that her TSH is significantly elevated at 8. How will you approach and manage her complaints? What discussion will you have with the patient regarding her therapy going forward?

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MODEL ANSWER

Advanced Pharmacology Discussion

            According to Thayakaran et al. (2019), subclinical hypothyroidism refers to thyroid-stimulating hormone (TSH) levels of 4.5 to 10 mlU/L. A normal level of TSH is 0.5 to 4.5, and full-blown | PLACE YOUR ORDER NOW AT writtask.com | elevated at 8, meaning it is full blown, thus the need to approach the patient in a way that allows effective management of her complaints. First, having studied her lab results, the approach I would adopt is that which involves changing the patient’s diet going forward as part of managing | PLACE YOUR ORDER NOW AT writtask.com | foods to consume such as vegetables (cabbage, kale, broccoli, spinach, and cauliflower), as emphasized by Persani et al. (2019). The approach would also influence how she is going to manage | PLACE YOUR ORDER NOW AT writtask.com | exploring various available options such as using radioactive iodine to slow down the growth of the thyroid, anti-thyroid medications to prevent overproduction of hormones, and beta-blockers to reduce the rapid rate of heartbeat.

Accordingly, a discussion with the patient about the therapy going forward would center on whether or not she will undergo surgery or take | PLACE YOUR ORDER NOW AT writtask.com | will be important to engage the patient about her thyroid; for instance, the patient should understand that once she chooses surgery to remove the thyroid (thyroidectomy), her body would no longer make | PLACE YOUR ORDER NOW AT writtask.com | engage the patient about the available medication known as | PLACE YOUR ORDER NOW AT writtask.com | Fitzgerald & Bean (2018), thyroid hormone pills can be used to replace the natural hormone, while helping maintain normal metabolism, and possibly reduce the risk of cancer. With this information, the patient will be able to make the necessary decisions going forward about her condition.

References

Fitzgerald, S. P., & Bean, N. G. (2018). Thyroid stimulating hormone (TSH) autoregulation reduces variation in the TSH response to thyroid hormones. Temperature, 5, 4, 380-389. https://www.tandfonline.com/doi/full/10.1080/23328940.2018.1513110

Persani, L., Cangiano, B., & Bonomi, M. (2019). The diagnosis and management of central hypothyroidism in 2018. Endocrine Connections, 8(2). https://ec.bioscientifica.com/view/journals/ec/8/2/EC-18-0515.xml

Thayakaran, R., Adderley, N. J., Sainsbury, C., Torlinska, B., Boelaert, K., Šumilo, D., Price, M., … Nirantharakumar, K. (2019). Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. BMJ (Clinical Research Ed, 366. https://www.bmj.com/content/366/bmj.l4892