A 65 year old male presents with a painful left finger unable to bend and is significantly swollen. He has a history of osteoarthritis.
1. OA is a disease of articular cartilage and subchondial bone in diarthrodial joints. Explain this.
2. What is the role osteophytes in OA?
3. How do NASAIDS affect OA?
4. How does weight loss affect OA?
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Why OA is a disease of articular cartilage and subchondral bone
Osteoarthritis (OA) is defined as a form of arthritis that affects many people, especially in old age. It occurs when the protective cartilage which cushions the ends of bones wears down with time. Additionally, the condition often happens joints in the hands, hips, spine, knees, and the articular cartilage of synovial joints | PLACE YOUR ORDER NOW AT writtask.com | synovial fluid in subchondral bone also witnesses pathophysiologic changes.
Role of osteophytes in OA
Osteophytes always tend to form when the joints are experiencing arthritis. It often destroys the cartilage, white, and flexible tissue, which lines one’s bones and allows the joints’ ease movement. Osteophytes is therefore important in OA as it helps increase the surface area of the damaged joint. Consequently, osteophytes will often limit the movement of the joints.
How NASAIDS affect OA
NASAIDS are drugs that are most prescribed for treating conditions like arthritis. Some of the over the counter NSAIDs often used include ibuprofen and aspirin. For OA, the drugs will inhibit chondrocyte proliferation, synthesis of collagen, and proteoglycan. The drugs can also help prevent the inflammation of pain and damage to joints. The drugs have also been effective for people that have OA due to their non-sedating properties | PLACE YOUR ORDER NOW AT writtask.com | has also shown that drugs can make the pain worse and lead to joint replacement.
How Weight loss affects OA
The loss of weight has been known to be an effective way to prevent the start of osteoarthritis, reduce the symptoms, and eventually improve the quality of | PLACE YOUR ORDER NOW AT writtask.com | demonstrated that reducing weight reduction is an effective way to reduce the risk of OA, especially in women. Besides, joint pain is often linked to body weight, and conditions like obesity are risk factors for osteoarthritis. Therefore, looking at weight reduces pressure…
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