ASSIGNMENT | Why did the scientists perform the study (i.e., description of background)?

Why did the scientists perform the study (i.e., description of background)?
● What was the hypothesis (or hypotheses) under investigation?
● What were the major results and did they support or negate the hypothesis? Which key techniques were used to achieve these results?
● Why are the results significant and do they point to further/future studies? In other words, why does this article matter and what should or could be done next

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Summary

The researchers in this PLACE YOUR ORDER NOW AT writtask.com | were motivated by the fact that PLACE YOUR ORDER NOW AT writtask.com | outcomes are mostly impended by PLACE YOUR ORDER NOW AT writtask.com | fibers can, however, help reduce the colonization resistance of pathogens as well as act as anti-inflammatory metabolites,

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Using 5-8 weeks old male and female mice as models of the study, the researchers administered xanthan gum to the mice’s diet and hence monitored the effect it had on the PLACE YOUR ORDER NOW AT writtask.com | researchers used the gene amplicon sequencing as well as the analysis of their short fatty acids. The mice were also subjected to antibiotics and then intentionally PLACE YOUR ORDER NOW AT writtask.com | the colonization was measured by monitoring the feces for CFU.

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The results showed that there was a positive correlation between the microbe gum administered and the reduction in the colonization PLACE YOUR ORDER NOW AT writtask.com | for this, according to the researchers, was that the administration of xanthan gum reduces colonization by maintaining the levels of microbiota during treatment with antibiotics. Furthermore, the gum could have altered the activity of the administered oral antibiotics.

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Why The Scientists Performed The Experiment

The purpose of undertaking the experiment was to demonstrate the importance of the dietary fiber Xanthan gum on reducing the colonization of microbiota and as well as the PLACE YOUR ORDER NOW AT writtask.com | was occasioned by the fact that dietary fiber has a myriad of micro-biota-mediated benefits especially in reducing the colonization of pathogens as well as against Clostridiodes difficile.

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Hypothesis Under Investigation

The hypothesis of this study was “Proper Manipulation of Microbes especially through diet may result in better resistance to colonization of pathogens and hence result in better clinical results,”

Major Results and How They Supported or Negated the Hypothesis

Using C57BL/6 mice as a model for the study, the scientists added 5% of xanthan gum to the mice’s diet and hence examined what happens to its microbiota. To examine this fact, a 165 rRNA gene amplicon sequencing, as well as short fatty acid analysis, was undertaken. The mice were administered with cefoperazone as well as a host of other antibiotics. It was then challenged with C. difficile and by using the CFU, colonization was monitored.

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The results showed that the administration of xanthan gum altered the activity of the mice as there was a reduction in the colonization of the C. difficile. This shows that the gum altered the susceptibility of the mice to C. difficile colonization as it maintains the microbiota in the course of administering PLACE YOUR ORDER NOW AT writtask.com | used to achieve the results include ensuring that the levels of microbiota were maintained in the course of treatment. Another one was closely monitoring the CFU for any possibilities of colonization. Significance of the Results

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