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Disorders of the Hemostasis Case Study

The case study is about Leona, a 52-years old woman, who is overweight, smokes, and has atherosclerosis. During her 2-week vacation, she flies to Sidney, where she is hospitalized three days after arrival because of the severe pain experienced as a result of the inflammation on her left calf. Deep vein thrombosis was …

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Hypercoagulation is a health condition that involves more than the normal blood clotting. In the case of a cut, the body creates a thickened mass of blood tissue, which limits bleeding. However, there are times that the body forms blood clots when not needed, exposing the body to health risks. Serious health problems, including death, can occur when the blood clots form in vital body organs such as the brain and the heart. Hypercoagulation is either inherited or acquired from the environment. The condition can also be caused by health problems such as cancer, surgery, trauma, obesity, immobility, and pregnancy. Therefore, the long traveling hours and the overweight condition contributed to the development of deep vein thrombosis (Tietjen & Collins, 2018). Acquired hypercoagulation emerged as a result of long immobility hours on the plane and Leona’s obese state, causing blood clots in the veins. The lady was also already at risk of developing deep vein thrombosis because of her excess body weight and smoking behavior. Therefore, the condition could …

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Atherosclerosis is among the health condition identified in the case study, affecting Leona. It is a disease in which plaque develops inside the arteries, blood vessels that transport oxygenated blood to the body parts. The plaque includes cholesterol, fat, calcium, alongside other substances in the blood. Plaque hardens over time, which narrows the arteries. Some of the severe health problems that can emerge because of Atherosclerosis are stroke, heart attack, and to some extent death. Increased activity and Adherent of platelets to the endothelial cells serve as a bridging process, which circulates progenitor cells and directs inflammatory cells to atherosclerosis sites (Lippi, Franchini & Favaloro, 2016). Platelets are also more likely to contribute …

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Muscle contraction is an essential factor in ensuring blood flows normally through the veins. Therefore, extended immobility, more so when seated can cause pooling of blood, which can result in stiffness, swelling, and discomfort (Tietjen & Collins, 2018). The pooling of blood, more specifically in the legs results in the formation of blood clots, hence increased blood coagulation. Atherosclerosis, as described above, lead to the development of plaque in the arteries. Blood coagulation usually increases in the artery …

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During her hospitalization, Leona received heparin therapy as a treatment for her health condition. The medication is an anticoagulant, which gives it the ability to limit the formation of harmful clots in the arteries. It does not dissolve the already formed blood clots, but prevent their enlargement, which protects the body from more severe problems. The medication, therefore, stopped Leona’s health condition from becoming worse. Leona was not given heparin tablets to take back to the hotel because of the medication’s nature (Lippi et al., 2016). The tablets are negatively charged, large and cannot pass the membrane for absorption, which makes it difficult to administer it orally. Heparin …

References

Lippi, G., Franchini, M., & Favaloro, E. J. (2016). Diagnostics of inherited bleeding disorders of secondary hemostasis: An easy guide for routine clinical laboratories. In seminars in thrombosis and hemostasis. Thieme Medical Publishers.

Tietjen, G. E., & Collins, S. A. (2018). Hypercoagulability and migraine. Headache: The Journal of Head and Face Pain, 58(1), 173-183.