ASSIGNMENT HELP | Define dementia of Alzheimer type (DAT) and describe the pathophysiology, clinical manifestations, evaluation and treatment.

Dementia of the Alzheimer Type (DAT) is a fatal and progressive neurodegenerative condition. DAT can be credited to several factors such as the amyloid toxicity, cholinergic dysfunction and intracellular neurofibrillary | PLACE YOUR ORDER NOW AT writtask.com | of these three aspects leads to the loss of neurons and synapses, which in turn causes atrophy in the affected regions of the | PLACE YOUR ORDER NOW AT writtask.com | disease that mostly affects people in the older population, especially those above the age of 65.

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It manifests itself by the deterioration in memory and cognitive functions, the inability to perform every day activities such as dressing, and a constant display of neuropsychiatric and behavioral | PLACE YOUR ORDER NOW AT writtask.com | of the neuropsychiatric symptoms are delusions and | PLACE YOUR ORDER NOW AT writtask.com | changes experienced by the individual include disinhibition, apathy, anxiety, aberrant motor activities, eating disorders, euphoria, irritability and depression.

The diagnostic process for DAT includes the use of formal mental status examination, neuroimaging, laboratory testing, history and physical | PLACE YOUR ORDER NOW AT writtask.com | all the tests a conclusive decision can only be arrived at by performing a histologic evaluation of the brain | PLACE YOUR ORDER NOW AT writtask.com | several history and standard neurological tests helps the diagnostician differentiate between the other possible forms of dementia such as the vascular dementia or the dementia of Lewy bodies from the Alzheimer’s disease.

The treatment protocols for patients with DAT are mainly safety and supportive measures especially when they can no longer take care of | PLACE YOUR ORDER NOW AT writtask.com | staff ted to focus on providing the patient with a safe, cheery and comfortable environment, which should bbe designed to reinforce | PLACE YOUR ORDER NOW AT writtask.com | medication prescribed to the patients’ aims to improve their cognitive and | PLACE YOUR ORDER NOW AT writtask.com | that fall into this category include cholinetratse inhibitors, memantine and donepezil.

References

MSD MANUAL. (n.d.). Alzheimer disease – Neurologic disorders – MSD manual professional edition. MSD Manual Professional Edition. https://www.msdmanuals.com/professional/neurologic-disorders/delirium-and-dementia/alzheimer-disease

Więckowska, A., Wichur, T., Godyń, J., Bucki, A., Marcinkowska, M., Siwek, A., … & Kazek, G. (2018). Novel multitarget-directed ligands aiming at symptoms and causes of Alzheimer’s disease. ACS Chemical Neuroscience9(5), 1195-1214. https://doi.org/10.1021/acschemneuro.8b00024

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